Rh sensitization is one reason it's important to see your doctor in the first trimester of pregnancy. The problems will tend to get worse with each Rh-positive pregnancy you have. This can cause the baby to have anemia, jaundice, or more serious problems. It takes a while to make antibodies that can affect the baby, so during your first pregnancy, the baby probably would not be affected.īut if you get pregnant again with an Rh-positive baby, the antibodies already in your blood could attack the baby's red blood cells. In most cases, your blood will not mix with your baby's blood until delivery. Rh sensitization can occur during pregnancy if you are Rh-negative and pregnant with a developing baby ( fetus) who has Rh-positive blood. What causes Rh sensitization during pregnancy? This immune system response is called Rh sensitization. If your blood mixes with Rh-positive blood, your immune system will react to the Rh factor by making antibodies to destroy it. If you are Rh-negative, your red blood cells do not have a marker called Rh factor on them. Topic Overview What is Rh sensitization during pregnancy?
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